
Vol. 9, No. 2, 2003 Page 1&2 
 
 
'Body burden': studies reveal ubiquity of  toxic chemicals in U.S.
 
 
 
 
Americans carry a toxic "body burden" of hundreds of synthetic 
chemicals and other contaminants, according to a new study by the 
Centers for Disease Control and Prevention (CDC).  
Jim Pirkle and colleagues, who conducted the study, collected urine 
and blood samples from approximately 2,500 volunteers across the 
country, testing participants for the presence of 116 different 
contaminants. They found all 116 of the chemicals (which included toxic 
metals, combustion byproducts, and byproducts of pesticides, insect 
repellents and herbicides) present in at least some portion of the study 
subjects, with many  present in more than half of the people they tested. 
(See related articles, Crime Times, 2003, Vol. 9, No. 2, Page 1  
and Crime Times, 2003, Vol. 9, No. 2, Page 2.)
Their data, the researchers say, paint "a mixed picture, some 
encouraging findings and some of concern." Among their findings:
- While the number of children aged one to five with very high lead 
levels has dropped from 4.4 to 2.2 percent since the early 1990s, more 
than 400,000 young children in America still have dangerously high 
levels.
 - More than half of nonsmokers over the age of three have 
detectable levels of cotinine, a byproduct of tobacco smoke, in their 
bloodstreams. Levels are more than twice as high in children as they are 
in adults, and higher in African-Americans than in other groups. Overall, 
however, levels have dropped by 50 percent or more in nonsmokers in 
every age group.
 - Levels of chlorpyrifos, an organophosphate pesticide widely used 
in residential settings until 2001, are twice as high in children as in 
adults. Levels of DDE, a metabolite of DDT (a pesticide banned in 
1973), are three times higher in Mexican Americans than in other groups. 
"Additionally," the researchers say, "DDE levels were clearly 
measurable in people aged 12 to 19 years, even though people in this age 
group were born after DDT was banned in the United States." However, 
they note, population levels of DDE are far lower than before 1990.
 - Phthalates, found in many cosmetics, household products and soft 
plastics, are present in a large percentage of the population. Levels of one 
particular phthalate, found in plastic products such as infant toys, were 
highest among children. These chemicals are believed to interfere with 
normal hormonal metabolism, increasing the risk of cancer or behavioral 
changes.
 - Levels of banned PCBs and dioxins were too low to detect in 
most people.
 
The researchers say that the reductions in levels of lead, cotinine, 
PCBs, and DDE are encouraging evidence that environmental regulation 
and education efforts are leading to drops in toxic exposure. However, 
other researchers say that overall, the CDC data are alarming. Says 
pediatrician and toxins expert Philip J. Landrigan, M.D., "The bottom 
line... is that a whole raft of synthetic chemicals that simply did not exist 
40 or 50 years ago is now in the bodies and in the bloodstreams of most 
Americans." 
In a related report, a study by the Environmental Working Group and 
Mt. Sinai's School of Community Medicine found 167 chemical 
contaminants in the urine and blood of nine study participants. Of these, 
the researchers say, 94 are toxic to the brain and nervous system, and 79 
can cause abnormal development. 
They add, "Subjects contained an average of 91 compounds, most of 
which did not exist 75 years ago.... Both studies [this one and the CDC 
study] reveal disturbing gaps in scientific understanding of 
environmental contaminants and in our system of regulatory safeguards." 
-----
National Report on Human Exposure to Environmental 
Chemicals, J. Pirkle et al., Centers for Disease Control and 
Prevention, January 31, 2003, http://www.cdc.gov. See also: "CDC 
releases most extensive assessment to date of Americans' exposure to 
environmental chemicals," http://www.cdc.gov. 
-- and --
"Body burden," Environmental Working Group, January 2003, 
http://www.ewg.org. 
and -- 
"Proof of burden," Ben Harder, Science News, Vol. 163, 
February 22, 2003.